Details of the animation/ movie /software: The animation starts by brief explanation of the virus replication cycle. However, our data suggest that cell cycle arrest may be a common strategy to favor virus production, since all influenza viruses share similar transcription, translation, and replication mechanisms. Influenza virus is transmitted from infected mammals through the air by sneezing. Influenza A virus is an RNA virus that encodes up to 11 proteins and this small coding capacity demands that the virus use the host cellular machinery for many aspects of its life cycle. Above: illustration of influenza virus life cycle or replication. Its function is believed to facilitate the transport of newly synthesised RNPs from the nucleus to the cytoplasm to accelerate virus production. Influenza infection and replication is a multi-step process: firstly the virus has to bind to and enter the cell, then deliver its genome to a site where it can produce new copies of viral proteins and RNA, assemble these components into new viral particles and finally exit the host cell. Influenza virus exploits cellular factors to complete each step of viral replication. The animation illustrates an example of this process using the influenza virus. This … At this point, protein spikes on the surface of a virus may bind to other proteins on the cells that line the respiratory tract. However, avian strains can recombine with strains from other species to create new strains that infect humans. The infection and replication is a multi-step process: Binding to and entering the cell; Delivering the genome to a site where it can produce new copies of viral proteins and RNA; Assembling these components into new viral particles; Exiting the host cell c. M2 inhibitors: The antiviral drugs such as- Amantadine and Rimantadine block a viral ion channel (M2 protein) and prevent the virus … ADVERTISEMENTS: In this article we will discuss about the replication of influenza viruses. Most productive viral infections follow similar steps in the virus replication cycle: attachment, penetration, uncoating, replication, assembly, and release (). See all RKM flu images SHORT EXPLANATION: At upper right, a virus particle lands on … Replication cycle. It is covered under three main headings 1) Initiation of infection 2) Replication and the expression of the virus genome 3) Release of the mature virions from the infected cells. The cell then endocytoses the virus. In the acidic environment of the endosomes, the virus changes shape and fuses its envelope with the … Is transmitted from infected mammals through the air by sneezing proteins that form a viral replication strains! 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