N-Heterocyclic carbene-catalyzed oxidations. Total Synthesis of Hoiamide A Using an Evans–Tishchenko Reaction as a Key Step. Dioxirane Oxidations of Compounds other than Alkenes. Hirofumi Tohma, Shinobu Takizawa, Tomohiro Maegawa, Yasuyuki Kita. Illuminating Silicon Surface Hydrosilylation: An Unexpected Plurality of Mechanisms. Bohua Long, Shoubin Tang, Ligong Chen, Shiwei Qu, Bo Chen, Junyang Liu, Anita R. Maguire, Zhuo Wang, Yuqing Liu, Hui Zhang, Zhengshuang Xu, Tao Ye.
A concise synthesis of (2S,3S)-BocAHPBA and (R)-BocDMTA, chiral building blocks for peptide-mimetic HIV protease inhibitors.
Other synthetic methods. Primary alcohols and strong oxidizing agents. Development of Efficient Nitroxyl Radical-Catalyzed Oxidation Systems —Selective Oxidation from Primary Alcohols to Carboxylic Acids—. Studies directed towards the synthesis of schisanartane and related complex nortriterpenoids: construction of models of the peripheral ABC and FGH segments of rubrifloradilactone C. Alioune Fall, Massene Sene, Mohamed Gaye, Generosa Gómez, Yagamare Fall.
-methyl-β-hydroxyvaline in the preparation of a depsipeptide.
Kiyotomi Kaneda, Kohki Ebitani, Tomoo Mizugaki, Kohsuke Mori. The use of potassium persulfate enables an aerobic oxidation of benzyl substrates to provide aryl carbonyl compounds including acetophenones, benzophenones, imides, and benzoic acids under mild conditions in the presence of pyridine. Another way of preparing carboxylic acids from alcohols and ketones is converting those into cyanohydrins followed by hydrolysis to produce ɑ-hydroxy acids: F Javier Aladro, Francisco M Guerra, F Javier Moreno-Dorado, Jesús M Bustamante, Zacarı́as D Jorge, Guillermo M Massanet. technique and obtained in good to excellent yields, which makes this protocol Surface carboxylation of porous regenerated cellulose beads by 4-acetamide-TEMPO/NaClO/NaClO2 system. Toward a benign strategy for the manufacturing of betulinic acid. Enantioselective total synthesis of the polyketide natural product (−)-EI-1941-2: a novel interleukin-1β converting enzyme (ICE) inhibitor.
Rakesh Ganorkar,, Amarnath Natarajan,, Ahmed Mamai, and. Nabyl Merbouh, James M. Bobbitt, Christian Brückner. N-Heterocyclic Carbene-Catalyzed Oxidation of Unactivated Aldehydes to Esters. Reduction & Oxidation Reactions of Carboxylic Acids, [ "article:topic", "authorname:wreusch", "showtoc:no" ].
We also acknowledge previous National Science Foundation support under grant numbers 1246120, 1525057, and 1413739. A Practical RuCl3-Catalyzed Oxidation Using Trichloroisocyanuric Acid As a Stoichiometric Oxidant under Mild Nonacidic Conditions. Chemoselective Catalytic Oxidation of 1,2-Diols to α-Hydroxy Acids Controlled by TEMPO–ClO2 Charge-Transfer Complex. A new ground state single electron donor for excess electron transfer studies in DNA. Structure–activity relationships of a series of isoxazoles. Isabel W. C. E. Arends, Roger A. Sheldon. Discovery of potent, soluble and orally active TRPV1 antagonists.
Jingjing Zhou, Bowen Gao, Zhengshuang Xu, and Tao Ye . Nitroxyl radical-catalyzed chemoselective alcohol oxidation for the synthesis of polyfunctional molecules. 2 publications.
Design and Concise Synthesis of Fully Protected Analogues of l-γ-Carboxyglutamic Acid. The fifth asks you to draw the product of a reaction selected from 48 possible combinations of carboxylic acids and reagents. Moloud Ghafouri, Majid Moghadam, Kheirollah Mehrani, Anahita Daneshvar. The third and fourth questions focus on the relative acidity of selected compounds. Selective Single-Step Oxidation of Amine to Cross-Azo Compounds with an Unhampered Primary Benzyl Alcohol Functionality. Diversity-oriented synthesis of enantiopure -Substituted Aliphatic Primary Alcohols to Carboxylic Acids.
Carlos Alegret,, Ferran Santacana, and.
Organocatalytic One-Pot Oxidative Cleavage of Terminal Diols to Dehomologated Carboxylic Acids. These will be described later. Highly Efficient Approach to Orthogonally Protected (2S,4R)- and (2S,4S)-4-Hydroxyornithine.
trans
Total syntheses of spiroviolene and spirograterpene A: a structural reassignment with biosynthetic implications. Babak Karimi, Hamid M. Mirzaei, Elham Farhangi. Geetha Velmourougane, Michael B. Harbut, Seema Dalal, Sheena McGowan, Christine A. Oellig, Nataline Meinhardt, James C. Whisstock, Michael Klemba, and Doron C. Greenbaum . Colloids and Surfaces A: Physicochemical and Engineering Aspects. O Gary E. Keck, Matthew B. Kraft, Anh P. Truong, Wei Li, Carina C. Sanchez, Noemi Kedei, Nancy E. Lewin and Peter M. Blumberg . Bo Jiang, Emmanuelle Drouet, Michel Milas, Marguerite Rinaudo. syn Here we report that single Rh atom sites, Rh1O5 anchored in micropores of HZSM-5, can catalyze oxidation of ethane by hydrogen peroxide in aqueous solution to form acetic acid and formic acid at a temperature ≤ 50 °C at a pressure of ethane at 1.5 bar. Enantioselective synthesis of β-amino alcohols and α-amino acids via a copper catalyzed addition of diorganozinc reagents to N-phosphinoylimines. Determination of the side-products formed during the nitroxide-mediated bleach oxidation of glucose to glucaric acid. Jennifer M. Galvin, Eric N. Jacobsen, Michael Palucki. Low Temperature Oxidation of Ethane to Oxygenates by Oxygen over Iridium-Cluster Catalysts. A Concise, Selective Synthesis of the Polyketide Spacer Domain of a Potent Bryostatin Analogue. Carboxylic acids are much more acidic in nature than other compounds containing a hydroxyl group. Aerobic Copper-Catalyzed Organic Reactions. Tse-Lok Ho, Mary Fieser, Louis Fieser, Rick Danheiser, William Roush, Janice Smith. Reduction to a 1º-alcohol takes place rapidly on treatment with the powerful metal hydride reagent, lithium aluminum hydride, as shown by the following equation. Paul A. Wender,, Alexander V. W. Mayweg, and. 2. Total Synthesis of (−)-Muraymycin D2 and Its Epimer. Nitriles undergo smooth oxidative hydration to amides when aqueous methanol is employed as solvent. General Synthesis of Amino Acid Salts from Amino Alcohols and Basic Water Liberating H2. Ligand-Free Ag(I)-Catalyzed Carboxylation of Terminal Alkynes with CO2. N Since acyl hypohalites are a source of electrophilic halogen, this reaction takes a different course when double bonds and reactive benzene derivatives are present. Proof of the Existence of an Unstable Amino Acid: Pleurocybellaziridine in Pleurocybella porrigens. Amos B. Smith, III,*, Patrick R. Verhoest,, Kevin P. Minbiole, and. Daisuke Ojima, Ayano Yasui, Koh Tohyama, Keita Tokuzumi, Eisuke Toriihara, Kayoko Ito, Arihiro Iwasaki, Tomohiko Tomura, Makoto Ojika, and Kiyotake Suenaga . Hirashima, A. Itoh, Synthesis, 2006, 1757-1759. Hisaaki Onoue, Tomomi Baba, Keiichi Konoki, Kohei Torikai, Makoto Ebine, Tohru Oishi.
Mimicking the active site of aldehyde dehydrogenases: stabilization of carbonyl hydrates through hydrogen bonds. The carbocation generated in Step 1 attracts a water molecule. Scott D. Rychnovsky,, Rajappa Vaidyanathan,, Thomas Beauchamp,, Rong Lin, and.